Endocrine Abstracts

Magnesium (Mg), the second most abundant intracellular cation of the human body, plays a crucial role in nerve and muscle function. Although a frequent electrolyte abnormality, hypomagnesaemia is one of the most underdiagnosed one, symptoms being present only when Mg levels decrease bellow 0.5 mmol/l, Among the various causes of Mg deficiency endocrine disorders are neither the most frequent nor the most studied. An exception is the implication of Mg in bone and calcium metabo...

Disorders of calcium metabolism arise in a familial or sporadic setting. The resulting hypo- or hypercalcemia can induce serious clinical features. Calcium sensing receptor (CaSR) plays a key role in maintaining this balance and its molecular investigation is useful to determine the nature of a certain condition or to choose the appropriate therapeutic approach.In the present study we reported two clinical cases. A 16-year-old patient had a mild hypercal...